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Visual system side effects caused by parasympathetic dysfunction after botulinum toxin type B injections.

Abstract
Botulinum toxin type B (BTX-B) has been approved by the Food and Drug Administration for the treatment of cervical dystonia. However, as with botulinum toxin type A (BTX-A) it has off-label uses, such as for hyperhidrosis, focal dystonias, spasticity, and facial wrinkles. BTX-B has also been shown to be a safe and effective alternative for patients who are resistant to BTX-A. The most commonly reported side effects include dry mouth and dysphagia. To date, there have been few reports of visual disturbances associated with BTX-B use. In this study, we report on three individual patients who received BTX-B and who subsequently developed parasympathetic dysfunction of the visual system after injections of BTX-B at remote sites.
AuthorsJordan Dubow, Angela Kim, Jerrold Leikin, Kirk Cumpston, Sean Bryant, Michael Rezak
JournalMovement disorders : official journal of the Movement Disorder Society (Mov Disord) Vol. 20 Issue 7 Pg. 877-80 (Jul 2005) ISSN: 0885-3185 [Print] United States
PMID15806568 (Publication Type: Case Reports, Journal Article)
CopyrightCopyright 2005 Movement Disorder Society.
Chemical References
  • rimabotulinumtoxinB
  • Botulinum Toxins
  • Botulinum Toxins, Type A
Topics
  • Adult
  • Autonomic Nervous System Diseases (complications)
  • Botulinum Toxins (adverse effects)
  • Botulinum Toxins, Type A
  • Female
  • Humans
  • Male
  • Movement Disorders (drug therapy)
  • Vision Disorders (chemically induced)

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