[Can various antibiotics be combined for treating salpingitis?].

Abstract

Despite the therapeutic progress, the possible consequences of salpingitis remains serious: they consist essentially of sterility and ectopic pregnancy. Unfortunately, the biological and etiological diagnosis encounter many difficulties: samples difficult to obtain, slowness of the laboratory. On the basis of the fact that infections of the Fallopians often involve several organisms, the clinician could begin active treatment from the outset versus enterobacteria, anaerobes and Chlamydia. In vitro investigation of imipenem-ofloxacin and imipenem-doxycycline associations versus Chlamydia trachomatis have demonstrated that imipenem has no anti-chlamydia activity. The addition of ofloxacin or oxydoxycycline has no antagonistic effect. These experimental findings justify the clinician's use of an association of imipenem/cilastine for the initial treatment of upper genital tract infection.

• Authors: J Orfila, F Haider
• Journal: Revue francaise de gynecologie et d'obstetrique (Rev Fr Gynecol Obstet) Vol. 87 Issue 3 Pg. 117-9 (Mar 1992) ISSN: 0035-290X [Print] France
• Vernacular Title: Peut-on associer différents antibiotiques pour soigner une salpingite?
• PMID: 1579795 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• Drug Combinations
• Imipenem
• Ofloxacin
• Doxycycline

Topics

• Doxycycline (administration & dosage, pharmacology, therapeutic use)
• Drug Combinations
• Female
• Humans
• Imipenem (administration & dosage, pharmacology, therapeutic use)
• Ofloxacin (administration & dosage, pharmacology, therapeutic use)
• Salpingitis (drug therapy, microbiology)