Efficacy of the KTP laser in the treatment of middle ear cholesteatoma.

Abstract

OBJECTIVE:

To evaluate whether ancillary use of the KTP (potassium titanyl phosphate) laser can diminish the rate of residual disease in intact canal wall cholesteatoma surgery.

STUDY DESIGN:

Prospective controlled parallel group study.

SETTING:

Two neighboring district general hospitals, one with a KTP laser and one without.

PATIENTS:

All patients undergoing staged intact canal wall surgery for cholesteatoma.

INTERVENTION:

Staged intact canal wall surgery for cholesteatoma.

MAIN OUTCOME MEASURE:

Presence or absence of residual disease at the second stage operation, performed at least 12 months after the first operation.

RESULTS:

Thirty-three patients underwent treatment without and 36 underwent treatment with the laser. Ten patients without laser treatment had residual disease, whereas one patient had residual disease after laser treatment (p = 0.003). After adjustment using logistic regression, treatment still has a significant effect on outcome (p = 0.013). The number needed to treat is four.

DISCUSSION:

Ancillary use of the KTP laser in cholesteatoma surgery is a treatment that significantly improves complete removal of disease.

• Authors: John W Hamilton
• Journal: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology (Otol Neurotol) Vol. 26 Issue 2 Pg. 135-9 (Mar 2005) ISSN: 1531-7129 [Print] United States
• PMID: 15793394 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial)

Topics

• Adolescent
• Adult
• Animals
• Child
• Cholesteatoma, Middle Ear (surgery)
• Ear Canal (surgery)
• Female
• Follow-Up Studies
• Humans
• Laser Therapy
• Male
• Middle Aged
• Postoperative Complications (etiology, surgery)
• Prospective Studies
• Recurrence
• Reoperation
• Risk Factors