[Detoxic, protein-synthesizing function and resistance of hepatocytes in patients with chronic diffuse liver diseases during the treatment with legalon].

Abstract

The article presents the findings of the study of Legalon influence on detoxic, protein-synthesizing liver function, the resistance of hepatocytes in patients with steatohepatitis, chronic toxic hepatitis, chronic viral hepatitis C with minimal activity and liver cirrhosis. It was established in the study that dose option of the medication in patients with chronic diffuse liver diseases should be based on the severity of hepatocyte dysfunction.

• Authors: I I Dehtiar'ova, I M Skrypnyk, M M Kozachok, T V Kuts
• Journal: Likars'ka sprava (Lik Sprava) Issue 8 Pg. 70-6 (Dec 2004) ISSN: 1019-5297 [Print] Ukraine
• Vernacular Title: Stan detoksykuiuchoï, bilkovosyntetychnoï funktsiĭ i rezystentnosti hepatotsytiv pry khronichnykh dyfuznykh zakhvoriuvanniakh pechinky v dynamitsi likuvannia legalonom.
• PMID: 15771078 (Publication Type: English Abstract, Journal Article)

Chemical References

• Lipid Peroxides
• Protective Agents
• Silymarin

Topics

• Chronic Disease
• Hepatocytes (drug effects, metabolism)
• Humans
• Inactivation, Metabolic (physiology)
• Lipid Peroxides (metabolism)
• Liver Diseases (drug therapy, etiology, metabolism)
• Protective Agents (therapeutic use)
• Protein Biosynthesis (drug effects)
• Silymarin (therapeutic use)