Abstract | OBJECTIVE: METHODS: We conducted a prospective cohort study of consecutive patients presenting for parathyroidectomy for the treatment of primary hyperparathyroidism. Twenty-three patients underwent assessment preoperatively and postoperatively. The Functional Outcomes of Sleep Questionnaire (FOSQ), the Epworth Sleepiness Scale (ESS), and a questionnaire of disease-specific symptoms were administered preoperatively, 2 weeks postoperatively, and 4 to 6 months postoperatively. The FOSQ assesses how sleepiness alters daytime performance, and the ESS reflects the degree of daytime sleepiness. RESULTS: All 23 patients achieved normocalcemia postoperatively. Although no significant changes were found in the overall scores for the FOSQ and ESS after parathyroidectomy, there was a significant decline in the overall mean incidence of disease-specific symptoms postoperatively (P <or=0.0001 after 2 weeks and P = 0.0020 after 4 to 6 months). The five disease-specific symptoms that significantly decreased in frequency postoperatively were (1) muscle weakness, (2) polydipsia, (3) dry skin and itching, (4) memory loss, and (5) anxiety. CONCLUSION:
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Authors | Regina Paloyan Walker, Edward Paloyan, Chellam Gopalsami |
Journal | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
(Endocr Pract)
2004 Sep-Oct
Vol. 10
Issue 5
Pg. 404-8
ISSN: 1530-891X [Print] United States |
PMID | 15760787
(Publication Type: Journal Article)
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Topics |
- Aged
- Disorders of Excessive Somnolence
(etiology, surgery)
- Female
- Humans
- Hyperparathyroidism
(complications, surgery)
- Male
- Middle Aged
- Muscle Weakness
(etiology, surgery)
- Parathyroidectomy
- Prospective Studies
- Wakefulness
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