Tacrolimus ointment for the treatment of severe facial plaque psoriasis.

Abstract

Recently, tacrolimus ointment has proved to be effective and well tolerated in patients with facial psoriasis. A few months ago we had the opportunity to treat a patient with tacrolimus ointment who had severe and recalcitrant plaque psoriasis of the face. This present case illustrates the impressive improvement of facial plaque psoriasis following 5 months of treatment with tacrolimus 0.1% ointment twice a day. Significant improvement of facial plaque psoriasis was seen after 1 month and complete clearance after 5 months of therapy. Based on the available literature and illustrated by the present case we may conclude that tacrolimus ointment 0.1% can be recommended as a first-line treatment for facial psoriasis.

• Authors: E B M Kroft, A Erceg, K Maimets, W Vissers, P G M van der Valk, P C M van de Kerkhof
• Journal: Journal of the European Academy of Dermatology and Venereology : JEADV (J Eur Acad Dermatol Venereol) Vol. 19 Issue 2 Pg. 249-51 (Mar 2005) ISSN: 0926-9959 [Print] England
• PMID: 15752305 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunosuppressive Agents
• Ointments
• Tacrolimus

Topics

• Administration, Topical
• Facial Dermatoses (drug therapy)
• Humans
• Immunosuppressive Agents (administration & dosage, therapeutic use)
• Male
• Middle Aged
• Ointments
• Psoriasis (drug therapy)
• Tacrolimus (administration & dosage, therapeutic use)