Abstract | PURPOSE OF REVIEW: Functional dyspepsia is a common disorder, most of the time of unknown etiology and with variable pathophysiology. Therapy has been and still is largely empirical. Data from recent studies provide new clues for targeted therapy based on knowledge of etiology and pathophysiologic mechanisms. RECENT FINDINGS: The role of Helicobacter pylori gastritis in the pathogenesis of functional dyspepsia has been defined: It is causative in a small minority of patients. Associations between (groups of) symptoms and pathophysiologic mechanisms have been established, but there is much overlap and interaction, and their relevance for the individual patient is uncertain, especially because of the variability of symptoms over time. Little progress has been made in pharmacotherapy of functional dyspepsia, but exploratory studies show interesting new options. Hypnotherapy seems a promising alternative. SUMMARY:
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Authors | Jan H Kleibeuker, Jaap C Thijs |
Journal | Current opinion in gastroenterology
(Curr Opin Gastroenterol)
Vol. 20
Issue 6
Pg. 546-50
(Nov 2004)
ISSN: 0267-1379 [Print] United States |
PMID | 15703680
(Publication Type: Journal Article)
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