Cutaneous Waldenstrom's macroglobulinemia with "deck-chair" sign treated with cyclophosphamide.

Abstract

Specific skin lesions are rare in Waldenstrom's macroglobulinemia (WM). We report a case of a 58-year-old man who presented macules, papules, and an erythema of the trunk with the "deck-chair" sign revealing the relapse of WM. Histologic and immunohistochemical examinations confirmed that cutaneous lesions were related to specific infiltration with neoplastic cells. Remission of both skin lesions and immunological abnormalities was obtained with oral cyclophosphamide.

• Authors: Julien Autier, Marc Buffet, Laure Pinquier, Anne-Isabelle Merlat-Guitard, Agnes Carlotti, Nathalie Franck, Isabelle Gorin, Nicolas Dupin
• Journal: Journal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 52 Issue 2 Suppl 1 Pg. 45-7 (Feb 2005) ISSN: 1097-6787 [Electronic] United States
• PMID: 15692513 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antineoplastic Agents, Alkylating
• Cyclophosphamide

Topics

• Antineoplastic Agents, Alkylating (therapeutic use)
• Cyclophosphamide (therapeutic use)
• Humans
• Male
• Middle Aged
• Skin Diseases (drug therapy, immunology, pathology)
• Waldenstrom Macroglobulinemia (drug therapy, immunology, pathology)