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[Cochlear-vestibular ototoxicity by gentamicin. Report of a case and literature review].

Abstract
Gentamicin is an antibiotic member of the aminoglycosides family with well known potential to cause permanent ototoxicity by damaging more likely the cochlea vestibular system. We are reporting the clinical case of a 48 year-old female who was treated with such IV drug because of abdominal surgery. She had no otologic past history, and was complaining of tinnitus, periferical vertigo and progressive bilateral neurosensorial hearing loss, it est, cochlear-vestibular symptoms. After the withdrawol of gentamicin, the vestibular pathologic symptoms but not the hearing loss had improved, docummented by the persistance of the audiometric decay in the acute frequencies. Prevention is the best way to avoid iatrogenic lesions with thesse climps.
AuthorsV Pino Rivero, M Marcos García, T Keituqwa Yáñez, A González Palomino, G Trinidad Ruiz, G Pardo Romero, A Blasco Huelva
JournalAnales otorrinolaringologicos ibero-americanos (An Otorrinolaringol Ibero Am) Vol. 31 Issue 6 Pg. 531-7 ( 2004) ISSN: 0303-8874 [Print] Spain
Vernacular TitleOtotoxicidad cócleo-vestibular por gentamicina. Caso clínico y revisión de la literatura.
PMID15663084 (Publication Type: Case Reports, English Abstract, Journal Article, Review)
Chemical References
  • Anti-Bacterial Agents
  • Gentamicins
Topics
  • Anti-Bacterial Agents (administration & dosage, adverse effects)
  • Cochlea (drug effects, physiopathology)
  • Female
  • Gentamicins (administration & dosage, adverse effects)
  • Hearing Loss, Sensorineural (chemically induced, diagnosis)
  • Humans
  • Injections, Intravenous
  • Middle Aged
  • Severity of Illness Index
  • Vestibule, Labyrinth (drug effects, physiopathology)

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