Abstract | OBJECTIVE: METHODS: Ninety-five patients with DPN from 4 hospitals in shanghai were randomly assigned to two groups: 49 cases in Neurotropin group (6 ml, IV, QD for 2 weeks, then, 2 tablets, BID for another 2 weeks). 46 cases in Methycobal group (1 ml, IM, QD for 2 weeks, then, 1 tablet TID for another 2 weeks. RESULTS:
Neurotropin significantly improved neuralgia in type 2 diabetes mellitus with DPN, the efficacy rate was 67.3% in the first week, and 87.0% in the 4th week, comparing with 34.8% and 68.5% in the control group. The efficacy rate for numbness was 58.7% in the study group after 4 weeks therapy, and 69.5% in control group. In the whole 4 weeks therapeutic course, neuralgia and numbness were improved in the two groups, and the improved rate in Neurotropin group is high than in the control group (P < 0.01). CONCLUSION:
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Authors | Guang Ning, Da-jin Zou, Wei Liu, Hui-li Xing, Wei Zhang, Yong-ju Zhao, Jin Lu, Hua Xu, Jie Jin |
Journal | Zhonghua yi xue za zhi
(Zhonghua Yi Xue Za Zhi)
Vol. 84
Issue 21
Pg. 1785-7
(Nov 02 2004)
ISSN: 0376-2491 [Print] China |
PMID | 15631774
(Publication Type: Clinical Trial, English Abstract, Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Analgesics
- Polysaccharides
- neurotropin
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Topics |
- Aged
- Analgesics
(therapeutic use)
- Diabetes Mellitus, Type 2
(drug therapy)
- Diabetic Neuropathies
(drug therapy)
- Female
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Neuralgia
(drug therapy)
- Polysaccharides
(therapeutic use)
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