Abstract | BACKGROUND/AIMS: METHODS: RESULTS: CONCLUSIONS:
Thioredoxin has a potential to attenuate hepatic fibrosis via suppressing oxidative stress and inhibiting proliferation of stellate cells.
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Authors | Hiroaki Okuyama, Hajime Nakamura, Yasuyuki Shimahara, Naoki Uyama, Yong-Won Kwon, Norifumi Kawada, Yoshio Yamaoka, Junji Yodoi |
Journal | Journal of hepatology
(J Hepatol)
Vol. 42
Issue 1
Pg. 117-23
(Jan 2005)
ISSN: 0168-8278 [Print] Netherlands |
PMID | 15629516
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Tumor Necrosis Factor-alpha
- Thioacetamide
- Thioredoxins
- Cycloheximide
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Topics |
- Animals
- Cell Proliferation
(drug effects)
- Cells, Cultured
- Cycloheximide
(pharmacology)
- Liver
(cytology)
- Liver Cirrhosis, Experimental
(chemically induced, prevention & control)
- Male
- Mice
- Mice, Inbred C57BL
- Oxidative Stress
- Rats
- Rats, Wistar
- Thioacetamide
(toxicity)
- Thioredoxins
(metabolism)
- Tumor Necrosis Factor-alpha
(pharmacology)
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