Abstract | BACKGROUND: OBSERVATIONS: A survey was mailed to 40 patients with symptomatic oral lichen planus treated with topical tacrolimus. Surveys were completed by 37 patients (93%) a mean of 1.3 years after initiation of treatment. Thirty-three (89%) of the 37 patients reported symptomatic improvement, and 31 (84%) reported partial to complete lesion clearance while using topical tacrolimus. On average, patients noted improvement in 1 month. Twelve patients (32%) reported adverse effects consistent with those reported previously (ie, burning, irritation, and tingling). Among the 28 patients still using the medication, 15 patients (54%) apply it at least once daily. Of the 9 patients who discontinued using the medication, 5 experienced recurrence. CONCLUSIONS:
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Authors | Julie A Byrd, Mark D P Davis, Alison J Bruce, Lisa A Drage, Roy S Rogers 3rd |
Journal | Archives of dermatology
(Arch Dermatol)
Vol. 140
Issue 12
Pg. 1508-12
(Dec 2004)
ISSN: 0003-987X [Print] United States |
PMID | 15611431
(Publication Type: Journal Article)
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Chemical References |
- Immunosuppressive Agents
- Tacrolimus
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Topics |
- Administration, Topical
- Adult
- Aged
- Aged, 80 and over
- Female
- Humans
- Immunosuppressive Agents
(administration & dosage, adverse effects, therapeutic use)
- Lichen Planus, Oral
(drug therapy, pathology)
- Male
- Middle Aged
- Recurrence
- Surveys and Questionnaires
- Tacrolimus
(administration & dosage, adverse effects, therapeutic use)
- Time Factors
- Treatment Outcome
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