Abstract | OBJECTIVES: Improve antibiotic therapies in a geriatrics hospital by enhancing guidelines impact. Historical background. - Study of the uses of the data-processing tool: detection of adverse drug events and inappropriate therapies; diffusion of the probable bacteria and their sensitivities to antibiotics following the infected site; creating decisional algorithms leading to suggested antibiotic therapy concept. METHOD: Referring to the conferences of consensus: drafting of local protocols of antibiotic therapies by using data processing if possible. Description of computer-systems implemented in Salt Lake City (USA) and Tubingen (Germany). With the assistance of an expert infectiologist, design of a database containing clinical details of the different situations in the pulmonary and urinary infections: once the clinical data are entered, a suggested antibiotic therapy appears on the screen, followed by a suggested prescription adapted to patient's specifications. During five years, survey of Defined Daily Dose per 1000 occupied bed-days; survey of sensitivities to antibiotics of urinary tract bacteria. RESULTS: Decrease of overall antibiotic consumption; decrease of broad-spectrum agents; modifications of E. coli sensitivities lead to variations of suggested antibiotic therapy. DISCUSSION: Seizure of the clinical determinants imposes a reducing effect; but it is necessary to apply to antibiotic therapies a hierarchicalbasis on account of bacterial resistances process and on account of "tonnage" of antibiotic prescriptions. CONCLUSION: Computer-assisted decision in antibiotic therapy can draw prescribers' attention to guidelines. The adhesion of the physicians to the computerized decision-making system is consolidated by their direct participation in the design of this system.
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Authors | C Obez, A-M Barisic, W Chatelier, M-C Dellamonica, J Falcot, C Koubi, V Mondain, P Dellamonica |
Journal | Pathologie-biologie
(Pathol Biol (Paris))
Vol. 52
Issue 10
Pg. 589-96
(Dec 2004)
ISSN: 0369-8114 [Print] France |
Vernacular Title | Les systèmes informatiques d'aide à la décision en antibiothérapie à propos d'une application en gériatrie. |
PMID | 15596308
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Aged
- Anti-Bacterial Agents
(therapeutic use)
- Drug Therapy, Computer-Assisted
(methods)
- Geriatrics
- Humans
- Infections
(drug therapy)
- Sensitivity and Specificity
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