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Gestrinone in the treatment of uterine leiomyomata: effects on uterine blood supply.

Abstract
Gestrinone has been shown to reduce uterine volume and stop bleeding in women with uterine leiomyomata. In the present study, we demonstrated a reduction in the volume of uterine myomas and in the uterine artery blood perfusion over a 6-month period of gestrinone administration in premenopausal women.
AuthorsAntonio La Marca, Simone Giulini, Giovanni Vito, Raoul Orvieto, Annibale Volpe, Valerio Maria Jasonni
JournalFertility and sterility (Fertil Steril) Vol. 82 Issue 6 Pg. 1694-6 (Dec 2004) ISSN: 0015-0282 [Print] United States
PMID15589885 (Publication Type: Clinical Trial, Journal Article)
Chemical References
  • Estrogen Antagonists
  • Gestrinone
Topics
  • Adult
  • Estrogen Antagonists (therapeutic use)
  • Female
  • Gestrinone (therapeutic use)
  • Humans
  • Leiomyomatosis (blood supply, diagnostic imaging, drug therapy)
  • Premenopause
  • Regional Blood Flow (drug effects)
  • Time Factors
  • Treatment Outcome
  • Ultrasonography
  • Uterine Neoplasms (blood supply, diagnostic imaging, drug therapy)

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