[Vitamin K and bone quality].

Abstract

Dietary vitamin K intakes becomes reduced with aging. Low vitamin K intakes are associated with an increased incidence of hip fractures and an increase of under carboxylated osteocalcin in elderly men and women. The increase of under carboxylated osteocalcin is a risk factor for fractures in osteoporosis. Vitamin K2 treatment is effective for the prevention of fractures, but not for the increase of bone mineral density in osteoporosis. Vitamin K2 administration could be a potential treatment to improve the bone quality.

• Authors: Hideaki Kishimoto
• Journal: Clinical calcium (Clin Calcium) Vol. 14 Issue 4 Pg. 621-6 (Apr 2004) ISSN: 0917-5857 [Print] Japan
• PMID: 15577021 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Vitamin A

Topics

• Aged
• Bone and Bones (drug effects, physiology)
• Female
• Fractures, Bone (prevention & control)
• Humans
• Osteoporosis (drug therapy)
• Vitamin A (pharmacology, therapeutic use)