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Ergot pharmacology and alternative delivery systems for ergotamine derivatives.

Abstract
Dihydroergotamine mesylate (DHE) has been used in migraine therapy since the 1940s. Renewed interest in its use has been kindled by research in receptor pharmacology and by efficacy of DHE-45 in breaking the cycle of chronic daily headache. Nasal and oral routes of administration may widen the applicability of DHE.
AuthorsJ Goldstein
JournalNeurology (Neurology) Vol. 42 Issue 3 Suppl 2 Pg. 45-6 (Mar 1992) ISSN: 0028-3878 [Print] United States
PMID1557192 (Publication Type: Journal Article, Review)
Chemical References
  • Dihydroergotamine
Topics
  • Dihydroergotamine (administration & dosage, pharmacology, therapeutic use)
  • Drug Administration Routes
  • Humans
  • Migraine Disorders (drug therapy)

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