[Long-term study "Neurodermatitis therapy using urea-containing Externa"].

Abstract

A long-term study on the therapy of atopic dermatitis with topical urea agents was conducted by over 400 practising dermatologists and pediatricians in Western Germany from March 1989 to March 1991. 1905 patients of all ages who had a baseline diagnosis of acute exacerbation of their neurodermatic skin condition were entered into this open, uncontrolled, multicenter study. Acute attacks were treated with a combination of hydrocortisone and urea. Once the acute symptoms had subsided, therapy was continued with a 10% urea ointment. Over the 12-month observational period, a total of 84% of the patients were exclusively treated with the two trial preparations and only 16% additionally required other corticosteroids.

• Authors: G Burkard, S Schmitt
• Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 43 Suppl 11 Pg. 13-7 ( 1992) ISSN: 0017-8470 [Print] Germany
• Vernacular Title: Langzeitstudie "Neurodermitis-Therapie mit harnstoffhaltigen Externa".
• PMID: 1555937 (Publication Type: Clinical Trial, English Abstract, Journal Article, Multicenter Study)

Chemical References

• Anti-Inflammatory Agents
• Drug Combinations
• Ointments
• Urea
• Hydrocortisone

Topics

• Administration, Topical
• Adolescent
• Adult
• Anti-Inflammatory Agents (administration & dosage)
• Child
• Child, Preschool
• Dermatitis, Atopic (drug therapy)
• Drug Combinations
• Female
• Humans
• Hydrocortisone
• Infant
• Longitudinal Studies
• Male
• Middle Aged
• Ointments
• Urea (administration & dosage)