[Spondylodiscitis caused by a strain of Staphylococcus aureus, in vitro sensitive to penicillin].

Abstract

The case history of a man referred to our department with the diagnosis of purulent meningitis; actually, he presented spondylodiscitis of the lumbar spine with the infection spreading into the spinal canal and the left psoas muscle. The disease was caused by a strain of Staphylococcus aureus, which in vitro was sensitive to penicillin. However, treatment with crystalline penicillin in combination with ciprofloxacin failed. The paper suggests a differential diagnosis permitting to distinguish a typical purulent meningitis and an abscess in the spinal canal. The authors also discuss the suitability of administering penicillin in staphylococcal sepsis caused by a sensitive strain. The authors do not recommend crystalline penicillin in the management of severe staphylococcal infections even in cases, where the isolated S. aureus strain is really sensitive to penicillin.

• Authors: Jirí Benes, Mária Kabelková, Jana Kotlíková, Petr Petrás, Jan Louda
• Journal: Klinicka mikrobiologie a infekcni lekarstvi (Klin Mikrobiol Infekc Lek) Vol. 10 Issue 5 Pg. 236-40 (Oct 2004) ISSN: 1211-264X [Print] Czech Republic
• Vernacular Title: Spondylodiscitida vyvolaná kmenem Staphylococcus aureus, in vitrro citlivým k penicilinu.
• PMID: 15558453 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Penicillin G
• Oxacillin

Topics

• Discitis (drug therapy, microbiology)
• Drug Resistance, Bacterial
• Humans
• Lumbar Vertebrae
• Male
• Microbial Sensitivity Tests
• Middle Aged
• Oxacillin (therapeutic use)
• Penicillin G (therapeutic use)
• Staphylococcal Infections (drug therapy, microbiology)
• Staphylococcus aureus (drug effects)