[A case of radiofrequency ablation therapy for recurrent hepatomas with tumor fever--efficacy of hepatic arterial infusion therapy with antibiotics and anticancer drugs].

Abstract

Efficacy of hepatic arterial infusion therapy (HAI) using antibiotics for hepatic abscess has been reported. However, we effectively performed RFA therapy after HAI with antibiotics and anticancer drugs for recurrent hepatomas with tumor fever. A 67-year-old female of recurrent hepatomas with fever is presented here. She was diagnosed with a 6 cm recurrent hepatoma, both in the right and IM lobes. Her liver function was child A with hepatitis C. On her CT scan, we found an enhanced 60 mm mass at an early phase and it was washed out at a delayed phase. Initially, we gave systemic medication of antibiotics, but could not decrease the fever. Therefore, we performed HAI with antibiotics and anticancer drugs. The patient's temperature went down after 14 days, and we were able to cut down her tumor size. After HAI, we were able to completely perform RFA for recurrent hepatomas.

• Authors: Shinji Uchida, Yuji Kawashima, Hiroyuki Horiuchi, Katsumi Hayashi, Kouji Okuda, Hisafumi Kinoshita, Shigeaki Aoyagi, Kazuo Shirouzu, Akira Yanase
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 31 Issue 11 Pg. 1819-21 (Oct 2004) ISSN: 0385-0684 [Print] Japan
• PMID: 15553726 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antineoplastic Agents
• Cilastatin
• Cefmetazole
• Imipenem
• Cisplatin

Topics

• Aged
• Antineoplastic Agents (administration & dosage)
• Carcinoma, Hepatocellular (therapy)
• Catheter Ablation
• Cefmetazole (administration & dosage)
• Cilastatin (administration & dosage)
• Cisplatin (administration & dosage)
• Female
• Fever (drug therapy)
• Hepatic Artery
• Humans
• Imipenem (administration & dosage)
• Infusions, Intra-Arterial
• Liver Neoplasms (therapy)
• Neoplasm Recurrence, Local