Abstract |
To investigate whether a C to G transversion at position 77 in exon A of the CD45 gene is associated with the development of diabetes mellitus type 1 (T1D), we studied 165 patients and 220 control individuals. The frequency of the 77G allele in the control group was 1.1%, which was not significantly different from the 1.2% found in the patient group (P = 0.922). The C to G transversion does not seem to be associated with susceptibility for T1D.
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Authors | H Thude, S Rosenhahn, W Hunger-Dathe, U-A Müller, D Barz |
Journal | European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics
(Eur J Immunogenet)
Vol. 31
Issue 6
Pg. 245-7
(Dec 2004)
ISSN: 0960-7420 [Print] England |
PMID | 15548260
(Publication Type: Journal Article)
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Chemical References |
- Leukocyte Common Antigens
- Protein Tyrosine Phosphatase, Non-Receptor Type 1
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Topics |
- Diabetes Mellitus, Type 1
(genetics, immunology)
- Exons
- Genetic Predisposition to Disease
- Genotype
- Germany
- Humans
- Leukocyte Common Antigens
(genetics, immunology)
- Point Mutation
- Protein Tyrosine Phosphatase, Non-Receptor Type 1
- Sequence Analysis, DNA
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