Laser in situ keratomileusis to correct post-keratoplasty astigmatism; 1-step versus 2-step procedure.

To investigate the correction of post-penetrating keratoplasty (PKP) astigmatism using laser in situ keratomileusis (LASIK). Visual and refractive outcomes were evaluated after LASIK was performed in 1 step (lamellar cut and ablation in 1 procedure) or 2 steps (lamellar cut then ablation in 2 successive procedures).
Department of Cornea and Refractive Surgery, Vissum-Instituto Oftalmológico de Alicante, University of Miguel Hernández, Alicante, Spain.
In this prospective observational study, 22 consecutive eyes were divided into 2 groups depending on the LASIK procedure performed to correct post-PKP astigmatism. Group 1 (1-step LASIK) included 11 eyes and Group 2 (2-step LASIK), 11 eyes. The patients were followed for 6 months.
A statistically significant improvement was obtained in Group 2 with a mean vector analysis result of the cylinder of -4.37 diopters (D) +/- 1.79 (SD) (P = .018). In Group 1, the mean astigmatism correction was 2.38 +/- 1.71 D. The number of reoperations and residual refractive defects were significantly better in Group 2.
The 2-step technique improved the accuracy of excimer laser correction of post-PKP astigmatism.
AuthorsJorge L Alió, Jaime Javaloy, Amr A Osman, Virgilio Galvis, Alejandro Tello, Hazem E Haroun
JournalJournal of cataract and refractive surgery (J Cataract Refract Surg) Vol. 30 Issue 11 Pg. 2303-10 (Nov 2004) ISSN: 0886-3350 [Print] United States
PMID15519079 (Publication Type: Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't)
  • Adolescent
  • Adult
  • Aged
  • Astigmatism (etiology, surgery)
  • Corneal Topography
  • Female
  • Graft Survival
  • Humans
  • Keratomileusis, Laser In Situ (methods)
  • Keratoplasty, Penetrating (adverse effects)
  • Male
  • Middle Aged
  • Postoperative Complications
  • Prospective Studies
  • Refraction, Ocular (physiology)
  • Safety
  • Treatment Outcome
  • Visual Acuity (physiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: