Abstract |
Latanoprost is a prostaglandin F2alpha analog that reduces intraocular pressure by 20-40% in adults with open-angle glaucoma. The efficacy and safety of this drug in children has not been widely reported. In our study we evaluated the effect of latanoprost in 14 children aged 12-18 years (mean 15 years): 10 patients with glaucoma juvenile (I group); 2 patients with secondary glaucoma because of uveitis recidivans and 2 patients with aniridia and albinismus (II group). In the I group the average IOP decrement was 9 mmHg or 36.5% (range 29-44%). In the II group the average IOP decrement was 6.5 mmHg or 23.5% (range 11-33%). In one child with aniridia after one year of treatment IOL rose again to 26 mmHg and antiglaucomatous surgery was necessary. Ocular side effects in children of latanoprost are mild.
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Authors | Beata Urban, Alina Bakunowicz-Lazarczyk, Małgorzata Mrugacz, Monika Oziebło-Kupczyk |
Journal | Klinika oczna
(Klin Oczna)
Vol. 106
Issue 1-2 Suppl
Pg. 243-4
( 2004)
ISSN: 0023-2157 [Print] Poland |
Vernacular Title | Skuteczność latanoprostu w jaskrze wieku dzieciecego. |
PMID | 15510514
(Publication Type: Journal Article)
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Chemical References |
- Antihypertensive Agents
- Prostaglandins F, Synthetic
- Latanoprost
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Topics |
- Adolescent
- Antihypertensive Agents
(therapeutic use)
- Child
- Female
- Glaucoma
(drug therapy, etiology, physiopathology)
- Humans
- Intraocular Pressure
(drug effects)
- Latanoprost
- Male
- Prostaglandins F, Synthetic
(therapeutic use)
- Retrospective Studies
- Treatment Outcome
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