[Surgical treatment of multiresistant lung tuberculosis].

Abstract

Drug resistance has become a major problem in the treatment of tuberculosis. Pulmonary resection in combination with chemotherapy appears to be an effective measure for the treatment of multi-drug resistant pulmonary tuberculosis. A retrospective review was performed of the medical and laboratory findings of 28 patients with multi-drug resistant tuberculosis who underwent pulmonary resection for pulmonary tuberculosis between January 1990 and December 2000 at La Maria Hospital, Medellín. Twenty-one of them had medical therapy before surgery; 14 patients underwent upper lobectomy and 10 patients pneumonectomy). The AFB negative sputum conversion rate was 88.9% (25/27) after surgery, during an average of 6 weeks. Bacteriological relapses were confirmed in 6 of 27, 4 of these 6 had AFB negative sputum. Twenty-eight patients had medical therapy after surgery. For selected patients, pulmonary resection in combination with chemotherapy should be considered an effective measure for treatment of multi-drug resistant pulmonary tuberculosis.

• Authors: Angela Tobón, Lizeth Paniagua, Marcela Henao, Vivian Arcila, José Maya, Fernando Bedoya, Bernardo Muñoz
• Journal: Biomedica : revista del Instituto Nacional de Salud (Biomedica) Vol. 24 Supp 1 Pg. 65-72 (Jun 2004) ISSN: 0120-4157 [Print] Colombia
• Vernacular Title: Cirugía en tuberculosis pulmonar multirresistente.
• PMID: 15495573 (Publication Type: English Abstract, Journal Article)

Topics

• Adolescent
• Adult
• Aged
• Drug Resistance, Multiple, Bacterial
• Female
• Humans
• Male
• Middle Aged
• Retrospective Studies
• Tuberculosis, Pulmonary (drug therapy, surgery)