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Comparative immobilization of wild felids in Thailand.

Abstract
We immobilized individuals of four free-ranging felid species, leopard cat (Prionailurus bengalensis), clouded leopard (Neofelis nebulosa), Asiatic golden cat (Catopuma temminckii), and marbled cat (Pardofelis marmorata) with ketamine hydrochloride and xylazine hydrochloride (KH-XH) and with tiletamine hydrochloride and zolazepam hydrochloride (TH-ZH) between March 1998 and July 2002. Mean (+/-SD) dose of KH and XH was 26.51+/-5.71 mg/kg and 1.89+/-0.43 mg/kg, respectively (n=25), and mean dose of TH-ZH was 11.61+/-3.39 mg/kg (n=28). Dose was significantly correlated with induction time (P<0.001) and duration of anesthesia (P<0.05), but not with recovery time. There were significant differences between the drug combinations in time to induction (P<0.03) and time to anesthesia (P<0.01); recovery times were not significantly different. We conclude that immobilization of these felids with TH-ZH and KH-XH is effective and safe, but TH-ZH is preferred because of the smaller volume of drug necessary for sedation, faster time to induction, and absence of prolonged muscle rigidity during anesthesia.
AuthorsLon I Grassman Jr, Sean C Austin, Michael E Tewes, Nova J Silvy
JournalJournal of wildlife diseases (J Wildl Dis) Vol. 40 Issue 3 Pg. 575-8 (Jul 2004) ISSN: 0090-3558 [Print] United States
PMID15465729 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Adrenergic alpha-Agonists
  • Anesthetics, Dissociative
  • Drug Combinations
  • Xylazine
  • Tiletamine
  • Ketamine
Topics
  • Adrenergic alpha-Agonists (administration & dosage)
  • Anesthetics, Dissociative (administration & dosage)
  • Animals
  • Animals, Wild
  • Dose-Response Relationship, Drug
  • Drug Combinations
  • Felidae (physiology)
  • Female
  • Immobilization (methods, veterinary)
  • Ketamine (administration & dosage, antagonists & inhibitors)
  • Male
  • Thailand
  • Tiletamine (administration & dosage)
  • Time Factors
  • Xylazine (administration & dosage, antagonists & inhibitors)

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