Abstract |
We immobilized individuals of four free-ranging felid species, leopard cat (Prionailurus bengalensis), clouded leopard (Neofelis nebulosa), Asiatic golden cat (Catopuma temminckii), and marbled cat (Pardofelis marmorata) with ketamine hydrochloride and xylazine hydrochloride (KH-XH) and with tiletamine hydrochloride and zolazepam hydrochloride (TH-ZH) between March 1998 and July 2002. Mean (+/-SD) dose of KH and XH was 26.51+/-5.71 mg/kg and 1.89+/-0.43 mg/kg, respectively (n=25), and mean dose of TH-ZH was 11.61+/-3.39 mg/kg (n=28). Dose was significantly correlated with induction time (P<0.001) and duration of anesthesia (P<0.05), but not with recovery time. There were significant differences between the drug combinations in time to induction (P<0.03) and time to anesthesia (P<0.01); recovery times were not significantly different. We conclude that immobilization of these felids with TH-ZH and KH-XH is effective and safe, but TH-ZH is preferred because of the smaller volume of drug necessary for sedation, faster time to induction, and absence of prolonged muscle rigidity during anesthesia.
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Authors | Lon I Grassman Jr, Sean C Austin, Michael E Tewes, Nova J Silvy |
Journal | Journal of wildlife diseases
(J Wildl Dis)
Vol. 40
Issue 3
Pg. 575-8
(Jul 2004)
ISSN: 0090-3558 [Print] United States |
PMID | 15465729
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Adrenergic alpha-Agonists
- Anesthetics, Dissociative
- Drug Combinations
- Xylazine
- Tiletamine
- Ketamine
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Topics |
- Adrenergic alpha-Agonists
(administration & dosage)
- Anesthetics, Dissociative
(administration & dosage)
- Animals
- Animals, Wild
- Dose-Response Relationship, Drug
- Drug Combinations
- Felidae
(physiology)
- Female
- Immobilization
(methods, veterinary)
- Ketamine
(administration & dosage, antagonists & inhibitors)
- Male
- Thailand
- Tiletamine
(administration & dosage)
- Time Factors
- Xylazine
(administration & dosage, antagonists & inhibitors)
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