Micromorphology of sialoliths in submandibular salivary gland: a scanning electron microscope and X-ray diffraction analysis.

Abstract

PURPOSE:

Sialoliths are common in the submandibular gland and its duct system. The exact cause of formation of a sialolith is still a matter of debate. The aim of this study was to analyze 6 sialoliths ultrastructurally to determine their development mechanism in the submandibular salivary glands.

MATERIALS AND METHODS:

Six sialoliths retrieved from the hilus and duct of the submandibular salivary glands of 6 patients with sialadenitis were analyzed ultrastructurally by scanning electron microscope and x-ray diffractometer.

RESULTS:

Scanning electron microscope revealed mainly irregular, partly rudely hexagonal, needle-like and plate-shaped crystals. The cross-section from the surface to the inner part of the sialoliths showed no organic material. X-ray diffraction showed that the sialoliths were composed of hydroxyapatite crystals. Energy dispersive x-ray microanalysis showed that all of the samples contained high levels of Ca and P, and small amounts of Mg, Na, Cl, Si, Fe, and K.

CONCLUSION:

The main structures of the submandibular sialoliths were found to be hydroxyapatite crystals. No organic cores were observed in the central parts of the sialoliths. In accordance with these preliminary results, sialoliths in the submandibular salivary glands may arise secondary to sialadenitis, but not via a luminal organic nidus.

• Authors: Oğuzcan Kasaboğlu, Nuray Er, Celal Tümer, Murat Akkocaoğlu
• Journal: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons (J Oral Maxillofac Surg) Vol. 62 Issue 10 Pg. 1253-8 (Oct 2004) ISSN: 0278-2391 [Print] United States
• PMID: 15452813 (Publication Type: Journal Article)

Chemical References

• Phosphorus
• Durapatite
• Calcium

Topics

• Calcium (analysis)
• Crystallography
• Durapatite (analysis)
• Female
• Humans
• Male
• Middle Aged
• Phosphorus (analysis)
• Salivary Duct Calculi (chemistry, ultrastructure)
• Salivary Gland Calculi (chemistry, ultrastructure)
• Sialadenitis (metabolism)
• X-Ray Diffraction