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Effectiveness of vagus nerve stimulation in epilepsy patients: a 12-year observation.

Abstract
A retrospective review of the safety, tolerability, and efficacy of vagus nerve stimulation (VNS) in 48 patients with intractable partial epilepsy was performed. Side effects were few and mild to moderate. Mean seizure frequency decreased by 26% after 1 year, 30% after 5 years, and 52% after 12 years with VNS treatment.
AuthorsB M Uthman, A M Reichl, J C Dean, S Eisenschenk, R Gilmore, S Reid, S N Roper, B J Wilder
JournalNeurology (Neurology) Vol. 63 Issue 6 Pg. 1124-6 (Sep 28 2004) ISSN: 1526-632X [Electronic] United States
PMID15452317 (Publication Type: Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., Review)
Topics
  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Electric Stimulation Therapy (adverse effects, instrumentation)
  • Electrodes, Implanted
  • Epilepsies, Partial (therapy)
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Patient Acceptance of Health Care
  • Patient Dropouts
  • Retrospective Studies
  • Treatment Outcome
  • Vagus Nerve (physiopathology)

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