Abstract |
The clinicopathologic and the flow cytometric DNA characteristics of 14 patients with sinonasal hemangiopericytomas are presented. Patient and tumor characteristics were similar to previously published series. Flow cytometric analysis revealed a diploid DNA pattern and low S-phase in 13 neoplasmas and an aneuploid DNA pattern with relatively high S-phase in one. Histopathologically, all diploid and low S-phase neoplasms displayed relatively uniform cellular features and low mitotic counts. All patients are alive and free of disease; one is still alive after a single recurrence. Our data suggest that sinonasal hemangiopericytomas are low-grade neoplasms as evidenced by their histomorphology and their DNA content. Recurrences are delayed and can be controlled.
|
Authors | A K el-Naggar, J G Batsakis, G M Garcia, M L Luna, H Goepfert |
Journal | Archives of otolaryngology--head & neck surgery
(Arch Otolaryngol Head Neck Surg)
Vol. 118
Issue 2
Pg. 134-7
(Feb 1992)
ISSN: 0886-4470 [Print] United States |
PMID | 1540341
(Publication Type: Journal Article)
|
Chemical References |
|
Topics |
- Adult
- Aged
- Aged, 80 and over
- DNA, Neoplasm
(analysis)
- Female
- Flow Cytometry
- Hemangiopericytoma
(genetics, pathology)
- Humans
- Male
- Middle Aged
- Nose Neoplasms
(genetics, pathology)
- Paranasal Sinus Neoplasms
(genetics, pathology)
|