Abstract |
A case is reported of a 15-year-old boy with prolidase deficiency and marked urinary excretion of the iminodipeptide gly-pro. Prolidase activity of erythrocytes against substrate glycyl- proline was deficient, but after blood transfusions this was increased to 15.7% of donor activity and declined to 12% and 3.4% of normal activity after 8 and 45 days, respectively. Urinary iminodipeptide levels following transfusion remained unaltered.
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Authors | E Berardesca, D Fideli, M Bellosta, K M Dyne, G Zanaboni, G Cetta |
Journal | The British journal of dermatology
(Br J Dermatol)
Vol. 126
Issue 2
Pg. 193-5
(Feb 1992)
ISSN: 0007-0963 [Print] England |
PMID | 1536787
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Dipeptides
- glycylproline
- Dipeptidases
- proline dipeptidase
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Topics |
- Adolescent
- Blood Component Transfusion
- Dipeptidases
(deficiency)
- Dipeptides
(urine)
- Foot Ulcer
(etiology, therapy)
- Humans
- Male
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