Gonadotropin releasing hormone agonist treatment for severe menorrhagia in patients with contraindications to surgery.

Abstract

Four patients with heavy menorrhagia, severe iron-deficiency anemia and contraindications to surgery were treated with a gonadotropin-releasing hormone agonist in a depot formulation. At 2 months of therapy they were all amenorrheic, and at 6 months the hematologic values had improved markedly. Gonadotropin-releasing hormone agonists may obviate emergency surgery in patients at high surgical risk or could constitute the first line of sequential therapeutic regimens, once general health conditions have improved.

• Authors: P Vercellini, A Ferrari, A D'Alberton, T Motta, R Maggi, P Molteni
• Journal: European journal of obstetrics, gynecology, and reproductive biology (Eur J Obstet Gynecol Reprod Biol) Vol. 45 Issue 1 Pg. 70-2 (Jun 16 1992) ISSN: 0301-2115 [Print] Ireland
• PMID: 1535604 (Publication Type: Case Reports, Journal Article)

Chemical References

• Goserelin
• Buserelin

Topics

• Adult
• Buserelin (analogs & derivatives, therapeutic use)
• Contraindications
• Female
• Goserelin
• Humans
• Hysterectomy
• Menorrhagia (drug therapy, surgery)
• Middle Aged