Abstract | BACKGROUND: OBJECTIVE: The objective was to raise awareness of the potential complication of localized sclerodermoid change secondary to vitamin B12 injections and to present a novel approach to its treatment. METHODS: RESULTS: We report the first non-European case of localized sclerodermoid reaction secondary to vitamin B12 injections. Our patient presented with disfiguring depression of the left upper arm following vitamin B12 injections for macrocytic anemia secondary to Crohn's disease. Histopathology showed findings similar to those seen in localized scleroderma. The patient was successfully treated with excision of diseased skin, local fat transfer, and complex repair with dramatic improvement at 5 months in contour and overall appearance.
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Authors | Julia Ho, Yadira Hurley Rothchild, Roberta Sengelmann |
Journal | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
(Dermatol Surg)
Vol. 30
Issue 9
Pg. 1252-5
(Sep 2004)
ISSN: 1076-0512 [Print] United States |
PMID | 15355372
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Adult
- Arm
- Female
- Humans
- Injections, Subcutaneous
- Scleroderma, Localized
(chemically induced, surgery)
- Vitamin B 12
(administration & dosage, adverse effects)
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