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Paroxysmal cold haemoglobinuria as a tardive complication of idiopathic myelofibrosis.

Abstract
Paroxysmal cold haemoglobinuria (PCH) is an autoimmune haemolytic anaemia caused by the Donath-Landsteiner antibody. It is classically described in association with chronic syphilis or after acute viral infections. We describe the first case of PCH presented as a late manifestation of advanced myelofibrosis associated with antiphospholipid syndrome, that promptly responded to high dosage of prednisone.
AuthorsMassimo Breccia, Gianna Maria D'Elia, Gabriella Girelli, Stefania Vaglio, Fabiana Gentilini, Sarlo Chiara, Giuliana Alimena
JournalEuropean journal of haematology (Eur J Haematol) Vol. 73 Issue 4 Pg. 304-6 (Oct 2004) ISSN: 0902-4441 [Print] England
PMID15347319 (Publication Type: Case Reports, Journal Article)
CopyrightCopyright Blackwell Munksgaard 2004.
Topics
  • Aged
  • Female
  • Hemoglobinuria, Paroxysmal (etiology)
  • Humans
  • Primary Myelofibrosis (etiology)

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