Skin rashes and stomatitis due to parenteral treatment of rheumatoid arthritis with sodium aurothiomalate.

Abstract

In a prospective study of 45 patients with rheumatoid arthritis mucocutaneous symptoms and signs were evaluated before and during treatment with intramuscular sodium aurothiomalate (Myocrisin). The work, performed in close collaboration between dermatology and rheumatology departments, showed that there was no significant increase in mucocutaneous side effects in patients with pre-existing mucocutaneous disease. It is concluded that pre-existing dermatitis is not a contraindication for treatment with gold salts and that a previous mucocutaneous reaction to gold salts is not an absolute contraindication for a new trial of chrysotherapy.

• Authors: A Svensson, J Theander
• Journal: Annals of the rheumatic diseases (Ann Rheum Dis) Vol. 51 Issue 3 Pg. 326-9 (Mar 1992) ISSN: 0003-4967 [Print] England
• PMID: 1533505 (Publication Type: Journal Article)

Chemical References

• Gold Sodium Thiomalate

Topics

• Adult
• Aged
• Arthritis, Rheumatoid (drug therapy)
• Drug Eruptions (etiology)
• Female
• Gold Sodium Thiomalate (administration & dosage, adverse effects)
• Humans
• Infusions, Parenteral
• Male
• Middle Aged
• Prospective Studies
• Stomatitis (chemically induced)