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Double-blind randomized trial of nicotinamide on early-onset diabetes.

AbstractOBJECTIVE:
To determine the efficacy of nicotinamide in inducing remission in early-onset insulin-dependent diabetes mellitus.
RESEARCH DESIGN AND METHODS:
This study was a double-blind, randomized clinical trial.
CONCLUSIONS:
Nicotinamide failed to induce remission or differences on beta-cell secretion between the two groups.
AuthorsC M Lewis, D M Canafax, J M Sprafka, J J Barbosa
JournalDiabetes care (Diabetes Care) Vol. 15 Issue 1 Pg. 121-3 (Jan 1992) ISSN: 0149-5992 [Print] United States
PMID1531328 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • C-Peptide
  • Glycated Hemoglobin A
  • Niacinamide
Topics
  • Blood Glucose Self-Monitoring
  • C-Peptide (blood)
  • Diabetes Mellitus, Type 1 (blood, drug therapy)
  • Double-Blind Method
  • Glycated Hemoglobin (analysis)
  • Humans
  • Niacinamide (therapeutic use)
  • Remission Induction

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