Thallium-pertechnetate subtraction scanning in the preoperative localization of an ectopic undescended parathyroid gland.

Abstract

Although bilateral exploration is highly effective in the treatment of primary hyperparathyroidism, minimally invasive parathyroidectomy has evolved into the procedure of choice when a single parathyroid lesion can be localized preoperatively. In this article, we discuss the utilization of thallium-pertechnetate subtraction scanning (TPSS) after technetium Tc-99m sestamibi scintigraphy failed to localize an ectopic parathyroid adenoma. Subsequently, radioguided resection of an undescended parathyroid adenoma inferior to the left submandibular gland was performed with surgical cure after a single procedure. This case report illustrates the importance of TPSS as a second-line modality in preoperative adenoma localization, thereby using minimally invasive techniques to successfully treat this patient's primary hyperparathyroidism.

• Authors: James Frydman, Jesus Bianco, Marc Drezner, Herbert Chen
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 29 Issue 9 Pg. 542-4 (Sep 2004) ISSN: 0363-9762 [Print] United States
• PMID: 15311119 (Publication Type: Case Reports, Journal Article)

Chemical References

• Radiopharmaceuticals
• thallium chloride
• Sodium Pertechnetate Tc 99m
• Thallium

Topics

• Choristoma (diagnostic imaging, surgery)
• Female
• Humans
• Hyperparathyroidism
• Middle Aged
• Minimally Invasive Surgical Procedures (methods)
• Parathyroid Diseases (diagnostic imaging, surgery)
• Parathyroid Glands
• Parathyroidectomy (methods)
• Preoperative Care (methods)
• Radionuclide Imaging
• Radiopharmaceuticals
• Sodium Pertechnetate Tc 99m
• Subtraction Technique
• Thallium
• Treatment Outcome