[Sexual dysfunction among 78 Moroccan male hemodialysis patients: clinical and endocrine study].

Abstract

PURPOSE:

To investigate the correlation between biochemical and endocrine variables with sexual disorders in 78 male patients on chronic hemodialysis at the Ibn Rochd University Hospital (Casablanca-Morocco).

METHODS:

Seventy-eight male hemodialysis patients with chronic renal failure were evaluated with regard to their sexual function. All patients answered a personal questionnaire on their sexual activity. Hormone (FSH, LH, prolactin, testosterone, and parathyroid hormone) and zinc and ferritin assays were also performed.

RESULTS:

The men reported erection (44.9%), libido (44.9%), ejaculation (26.8%), and orgasm (21.8%) disorders. Gynecomastia was observed in 17.9% of the patients. There was no correlation with weight nor the nature of the causal nephropathy nor with duration of dialysis. Levels of gonadotropins (FSH, LH), prolactin, and parathyroid hormone were elevated. Testosterone levels were low. Ferritinemia was elevated but there was no significant variation in zincemia. There was a negative curvilinear relationship between serum testosterone and sexual disorders, and between gynecomastia and ferritinemia. LH and prolactin levels were positively correlated with gynecomastia.

CONCLUSION:

Abnormal hormonal and iron overload could be important factors involved in the complex pathogenesis of sexual dysfunction in chronic renal failure patients undergoning hemodialysis.

• Authors: M Zamd, M Farh, O Hbid, M Zabari, M Benghanem Gharbi, B Ramdani, D Zaïd, N El Abbadi, K Lalaoui, A Belhouari, E Hassan Tahri
• Journal: Annales d'endocrinologie (Ann Endocrinol (Paris)) Vol. 65 Issue 3 Pg. 194-200 (May 2004) ISSN: 0003-4266 [Print] France
• Vernacular Title: Troubles sexuels chez 78 hémodialysés chroniques marocains de sexe masculin: étude clinique et endocrinienne.
• PMID: 15277975 (Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Parathyroid Hormone
• Testosterone
• Prolactin
• Luteinizing Hormone
• Follicle Stimulating Hormone
• Ferritins
• Zinc

Topics

• Adult
• Erectile Dysfunction (blood, epidemiology)
• Ferritins (blood)
• Follicle Stimulating Hormone (blood)
• Gynecomastia (blood, epidemiology)
• Humans
• Iron Overload (complications)
• Kidney Failure, Chronic (complications, therapy)
• Luteinizing Hormone (blood)
• Male
• Middle Aged
• Morocco
• Parathyroid Hormone (blood)
• Prolactin (blood)
• Renal Dialysis (adverse effects)
• Sexual Dysfunction, Physiological (epidemiology, etiology)
• Surveys and Questionnaires
• Testosterone (blood)
• Zinc (blood)