Abstract | OBJECTIVES: BACKGROUND: Follow-up data on patients with junctional ectopic tachycardia suggest that this potentially lethal arrhythmia may cease spontaneously in a significant proportion of affected children. Therefore, temporary antiarrhythmic treatment appears to be the therapy of choice. METHODS: The efficacy of propafenone was prospectively assessed in four infants with junctional ectopic tachycardia (ventricular rate 180, 185, 210 and 320 beats/min, respectively). The diagnosis of junctional ectopic tachycardia was established before the age of 2 months in all four infants. Propafenone was given orally in a mean dose of 350 (300 to 500) mg/m2 body surface area per day. Success of therapy was determined by serial electrocardiograms (ECGs) and Holter ambulatory ECG monitoring. RESULTS: CONCLUSIONS:
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Authors | T Paul, A Reimer, J Janousek, H C Kallfelz |
Journal | Journal of the American College of Cardiology
(J Am Coll Cardiol)
Vol. 20
Issue 4
Pg. 911-4
(Oct 1992)
ISSN: 0735-1097 [Print] United States |
PMID | 1527301
(Publication Type: Case Reports, Clinical Trial, Journal Article)
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Chemical References |
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Topics |
- Drug Evaluation
- Electrocardiography
(methods)
- Electrocardiography, Ambulatory
- Follow-Up Studies
- Humans
- Infant
- Infant, Newborn
- Male
- Propafenone
(administration & dosage, therapeutic use)
- Prospective Studies
- Tachycardia, Ectopic Junctional
(congenital, drug therapy, epidemiology)
- Time Factors
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