[Short treatment of donovanosis with azithromycin].

Abstract

INTRODUCTION:

Azithromycine is recommended in the treatment of donovanosis with a 7-day treatment cycle. We report the efficacy of a single cure of 1 gram in two patients.

OBSERVATIONS:

Four patients, presenting with donovanosis, were treated with azithromycine according to 2 regimens. The first used 500 mg/d the molecule during 1 week, the second used azithromycine in single cure of 1 gram. The latter led to the complete cure of 2 patients.

DISCUSSION:

Many antibiotics are used in the treatment of donovanosis. Since 1996, Australian authors have used azithromycine in this indication. A single dose of this molecule appears effective in recent and confined donovanosis.

• Authors: E Clyti, P Couppié, M Strobel, C Cazanave, D Sainte-Marie, R Pradinaud
• Journal: Annales de dermatologie et de venereologie (Ann Dermatol Venereol) Vol. 131 Issue 5 Pg. 461-4 (May 2004) ISSN: 0151-9638 [Print] France
• Vernacular Title: Traitement court de la donovanose par l'azithromycine.
• PMID: 15235534 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Azithromycin

Topics

• Adult
• Aged
• Anti-Bacterial Agents (administration & dosage)
• Azithromycin (administration & dosage)
• Granuloma Inguinale (drug therapy)
• Humans
• Male