Abstract | INTRODUCTION: Azithromycine is recommended in the treatment of donovanosis with a 7-day treatment cycle. We report the efficacy of a single cure of 1 gram in two patients. OBSERVATIONS: Four patients, presenting with donovanosis, were treated with azithromycine according to 2 regimens. The first used 500 mg/d the molecule during 1 week, the second used azithromycine in single cure of 1 gram. The latter led to the complete cure of 2 patients. DISCUSSION: Many antibiotics are used in the treatment of donovanosis. Since 1996, Australian authors have used azithromycine in this indication. A single dose of this molecule appears effective in recent and confined donovanosis.
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Authors | E Clyti, P Couppié, M Strobel, C Cazanave, D Sainte-Marie, R Pradinaud |
Journal | Annales de dermatologie et de venereologie
(Ann Dermatol Venereol)
Vol. 131
Issue 5
Pg. 461-4
(May 2004)
ISSN: 0151-9638 [Print] France |
Vernacular Title | Traitement court de la donovanose par l'azithromycine. |
PMID | 15235534
(Publication Type: Case Reports, English Abstract, Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- Azithromycin
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Topics |
- Adult
- Aged
- Anti-Bacterial Agents
(administration & dosage)
- Azithromycin
(administration & dosage)
- Granuloma Inguinale
(drug therapy)
- Humans
- Male
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