[Sclerotherapy with OK-432 for cystic tumors in the neck region].

Abstract

BACKGROUND:

The intralesional injection of OK-432 has been proposed as an effective treatment of lymphangiomas and ranulas. The aim of this study was to review our experience with sclerotherapy of benign cervical cysts as an alternative method to surgical extirpation.

PATIENTS AND METHODS:

We performed a case note review of six patients who received OK-432 injections in a concentration of 0.01 mg/ml between March 2002 and December 2003.

RESULTS:

Disappearance of the lesions was achieved after one to three injections in all patients. We found a complete remission in two of six patients and a marked reduction in four of six patients. There were no significant complications observed.

CONCLUSION:

OK-432 is an effective alternative in the treatment of benign cervical cysts, but it is very important to exclude malignancy-associated diseases before instillation of OK-432. Long-term results will be awaited.

• Authors: M Bloching, G Götze, M Passmann, K Neumann
• Journal: HNO (HNO) Vol. 53 Issue 3 Pg. 238-42 (Mar 2005) ISSN: 0017-6192 [Print] Germany
• Vernacular Title: Sklerotherapie zystischer Raumforderungen im Halsbereich mit OK-432.
• PMID: 15221083 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antineoplastic Agents
• Picibanil

Topics

• Adolescent
• Adult
• Antineoplastic Agents (administration & dosage)
• Cysts
• Female
• Head and Neck Neoplasms (therapy)
• Humans
• Injections, Intralesional
• Male
• Middle Aged
• Picibanil (administration & dosage)
• Sclerotherapy (methods)
• Treatment Outcome