Abstract | AIM: METHODS: We describe a clinical case of a male aged 53 years, who was a heavy smoker for 30 years and a mason working with vibrating tools since 1962. He presented with a history of 10 years of attacks of vasospasm, functional impairment and digital ulceration. He was diagnosed as having hand-arm vibration syndrome vascular stage 4 on the Stockholm Workshop 1986 Scale. Besides suspension from work and abstention from smoking, we began intravenous infusion of iloprost for 6 h in cycles of 3-6 consecutive days, arriving at a dose of 1.5-2.0 ng/kg/min. RESULTS: After eight cycles, he reported significant symptomatic and functional improvement. Iloprost was seen to be efficacious: the trophic skin lesions disappeared and his microcirculatory perfusion tests improved. There were no significant side effects. CONCLUSIONS:
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Authors | Michele Meloni, Mario Torrazza, Roberto Ledda |
Journal | Occupational medicine (Oxford, England)
(Occup Med (Lond))
Vol. 54
Issue 4
Pg. 261-4
(Jun 2004)
ISSN: 0962-7480 [Print] England |
PMID | 15190165
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Vasodilator Agents
- Iloprost
|
Topics |
- Arm
(blood supply)
- Arm Injuries
(drug therapy, physiopathology)
- Hand
(blood supply)
- Hand Injuries
(drug therapy, physiopathology)
- Humans
- Iloprost
(administration & dosage)
- Infusions, Intravenous
- Male
- Microcirculation
- Middle Aged
- Occupational Diseases
(drug therapy, physiopathology)
- Treatment Outcome
- Vasodilator Agents
(administration & dosage)
- Vibration
(adverse effects)
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