Chronic ulcerative stomatitis associated with stratified epithelial specific antinuclear antibodies. A case report of a newly described disease entity.

Abstract

A case of erosive oral lesions associated with an unusual direct and indirect immunofluorescent pattern is presented. Rather than a submucosal band or intramucosal intercellular deposition, the pattern is that of an antinuclear antibody that reacts only with stratified epithelium. The clinical similarity of this case to erosive lichen planus is discussed. The usefulness of direct and indirect immunofluorescence techniques in the diagnosis of erosive oral lesions is stressed.

• Authors: L F Church Jr, R H Schosser
• Journal: Oral surgery, oral medicine, and oral pathology (Oral Surg Oral Med Oral Pathol) Vol. 73 Issue 5 Pg. 579-82 (May 1992) ISSN: 0030-4220 [Print] United States
• PMID: 1518645 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antibodies, Antinuclear
• Dexamethasone

Topics

• Aged
• Antibodies, Antinuclear (analysis)
• Chronic Disease
• Dexamethasone (therapeutic use)
• Diagnosis, Differential
• Epithelium (immunology)
• Female
• Fluorescent Antibody Technique
• Gingivitis, Necrotizing Ulcerative (diagnosis, drug therapy, immunology)
• Humans
• Lichen Planus (diagnosis)
• Mouth Mucosa (immunology)