[Medullary carcinoma of the thyroid gland: effect of postoperative transcutaneous radiotherapy on local control and results of treatment].

Abstract

In the period of Octo. 01, 1987. up to Dec. 31, 1998. retrospective-prospective, non-randomized study was conducted at IORS, which included 36 patients diagnosed with thyroid gland medullar cancer. Our study had the following aims: evaluation of treatment results following probability of total survival, survival without signs of disease and disease-free interval until local recurrence of the disease and influence of parameters of transcutaneous radiotherapy (intensity of total tumor dose and length of disease-free interval from date of performed operation to beginning of radiotherapy). After finished treatment, median of the patient follow-up was 37.75 months (3.5 up to 141 months); probability of total five-year survival was 62.61% and of 10 year survival was 23.48%. Probability of 5-year survival, without signs of disease was 37.13%, and of 10-year survival 18.56%. As to radiotherapy parameters intensity of total therapy dose was statistically insignificant, while time interval to beginning of transcutaneous radiotherapy, shorter than 2 months, was statistically significant in relation to prognosis of disease outcome.

• Authors: V Stanković, N Borojević, R Dzodić, I Golubicić
• Journal: Acta chirurgica Iugoslavica (Acta Chir Iugosl) Vol. 50 Issue 3 Pg. 125-30 ( 2003) ISSN: 0354-950X [Print] Serbia
• Vernacular Title: Medularni karcinom stitaste zlezde: uticaj postoperativne transkutane zracne terapije u lokalnoj kontroli i rezultatima lecenja.
• PMID: 15179768 (Publication Type: English Abstract, Journal Article)

Topics

• Adult
• Aged
• Carcinoma, Medullary (mortality, radiotherapy, surgery)
• Female
• Humans
• Male
• Middle Aged
• Neoplasm Recurrence, Local (prevention & control)
• Prospective Studies
• Radiotherapy Dosage
• Radiotherapy, Adjuvant
• Retrospective Studies
• Survival Rate
• Thyroid Neoplasms (mortality, radiotherapy, surgery)
• Thyroidectomy