Hepatocellular carcinoma in a case of Dubin-Johnson syndrome treated successfully with a central bilateral segmentectomy.

Abstract

A 72-year-old woman with hepatocellular carcinoma and HCV cirrhosis combined with Dubin-Johnson syndrome was successfully treated by a central bilateral segmentectomy. While the preoperative serum bilirubin level is one of the established criteria for determining the indications for a hepatic resection, it is not effective for HCV cirrhosis cases associated with Dubin-Johnson syndrome. Postoperative hyperbilirubinemia may be cured without special treatment such as bilirubin absorption or plasma exchange, but such patients must be carefully observed to ensure that liver failure does not occur.

• Authors: Yasunori Shikada, Takashi Matsumata, Taketoshi Suehiro, Keizo Sugimachi
• Journal: Hepato-gastroenterology (Hepatogastroenterology) 2004 May-Jun Vol. 51 Issue 57 Pg. 833-6 ISSN: 0172-6390 [Print] Greece
• PMID: 15143928 (Publication Type: Case Reports, Journal Article)

Topics

• Aged
• Carcinoma, Hepatocellular (complications, surgery)
• Female
• Hepatectomy (methods)
• Humans
• Jaundice, Chronic Idiopathic (complications, surgery)
• Liver Neoplasms (complications, surgery)
• Male
• Middle Aged
• Remission Induction