Successful treatment of a primary cutaneous zygomycosis caused by Absidia corymbifera in a premature newborn.

Abstract

Mucormycosis (zygomycosis) normally occurs among individuals with predisposing factors such as prematurity, use of broad spectrum antibiotics, metabolic acidosis or advanced stages of immunosuppression. There have been reports of sporadic cases of cutaneous mucormycosis related to predisposing skin lesions and contact with contaminated material such as adhesive bandages and tongue depressors placed close to intravenous catheter insertion sites. We report successful treatment of a case of Absidia corymbifera infection with the combination of amphotericin B and surgical debridement of the affected area.

• Authors: José Juan Morales-Aguirre, Wilson Martín Agüero-Echeverría, María Elena Ornelas-Carsolio, Jesús Reséndiz-Sánchez, Demóstenes Gómez-Barreto, Miguel Cashat-Cruz
• Journal: The Pediatric infectious disease journal (Pediatr Infect Dis J) Vol. 23 Issue 5 Pg. 470-2 (May 2004) ISSN: 0891-3668 [Print] United States
• PMID: 15131477 (Publication Type: Journal Article, Review)

Chemical References

• Antifungal Agents
• Amphotericin B

Topics

• Absidia (drug effects, isolation & purification)
• Amphotericin B (therapeutic use)
• Antifungal Agents (therapeutic use)
• Debridement (methods)
• Dermatomycoses (drug therapy, microbiology, surgery)
• Female
• Humans
• Infant, Newborn
• Infant, Premature
• Infant, Premature, Diseases (drug therapy, microbiology, surgery)
• Mucormycosis (drug therapy, microbiology, surgery)
• Treatment Outcome