Abstract | PURPOSE OF REVIEW: RECENT FINDINGS: SUMMARY: The use of metformin in early pregnancy for reducing the risk of miscarriage should be avoided outside of the context of properly designed prospective randomized trials. Safety in early pregnancy appears to be reassuring but not completely proven. The use of metformin in mid-pregnancy for gestational diabetes appears more logical but also needs adequate trials before general use is advocated.
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Authors | Robert J Norman, Jim X Wang, William Hague |
Journal | Current opinion in obstetrics & gynecology
(Curr Opin Obstet Gynecol)
Vol. 16
Issue 3
Pg. 245-50
(Jun 2004)
ISSN: 1040-872X [Print] England |
PMID | 15129054
(Publication Type: Journal Article, Review)
|
Chemical References |
- Hypoglycemic Agents
- Metformin
|
Topics |
- Abortion, Spontaneous
(prevention & control)
- Diabetes, Gestational
(drug therapy)
- Female
- Humans
- Hypoglycemic Agents
(adverse effects)
- Metformin
(adverse effects)
- Polycystic Ovary Syndrome
(drug therapy)
- Pregnancy
- Randomized Controlled Trials as Topic
|