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Multimodal treatment for resectable epithelial type malignant pleural mesothelioma.

AbstractBACKGROUND:
Malignant pleural mesothelioma is a rare malignancy. The outcome remains poor despite complete surgical resection.
PATIENTS AND METHODS:
Eleven patients with histologicaly proven epithelial type malignant pleural mesothelioma undergoing extrapleural pneumonectomy with systemic chemotherapy and/or radiotherapy before and after surgical resection were retrospectively reviewed.
RESULTS:
Ten out of 11 patients underwent complete surgical resection, of these 7 patients had stage I disease. Of these 7 patients, 5 are alive without any recurrence, a 2-year survival rate of 80% was observed in this group. There was no operative mortality or morbidity.
CONCLUSION:
Extrapleural pneumonectomy with perioperative adjuvant treatment is safe and effective procedure for epithelial type malignant pleural mesothelioma.
AuthorsIchiro Yoshino, Masafumi Yamaguchi, Tatsuro Okamoto, Chie Ushijima, Yasuro Fukuyama, Yukito Ichinose, Yoshihiko Maehara
JournalWorld journal of surgical oncology (World J Surg Oncol) Vol. 2 Pg. 11 (May 05 2004) ISSN: 1477-7819 [Electronic] England
PMID15128453 (Publication Type: Journal Article)

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