Abstract |
The aim of this retrospective study was to assess the incidence and aetiology of central and peripheral venous catheter (C/ PVC) infections during a 2-year period (1999-2000) and to determine the susceptibility of isolated microorganisms to various antimicrobial agents. Catheter tips were processed using the semiquantitative method and blood cultures were performed with the BacT/Alert automated system. Antibiotic susceptibilities were performed by disk agar diffusion and MICs were determined by Etest, according to NCCLS standards. During the study period, samples from 1039 C/ PVC infections were evaluated, yielding 384 (37.0%) positive cultures. Blood cultures were also available from 274 patients, of which 155 (56.6%) yielded the same microorganism as from the catheter. No bloodstream infections were detected in 104 C/ PVC-positive cases. Methicillin-resistant coagulase-negative staphylococci were the most frequent isolates, followed by Gram-negative bacteria, especially Pseudomonas aeruginosa. Resistance to glycopeptides among staphylococci and enterococci was not detected, whereas 60% of Gram-negative bacilli were resistant to beta-lactams.
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Authors | M Paragioudaki, V Stamouli, F Kolonitsiou, E D Anastassiou, G Dimitracopoulos, I Spiliopoulou |
Journal | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
(Clin Microbiol Infect)
Vol. 10
Issue 5
Pg. 431-5
(May 2004)
ISSN: 1198-743X [Print] England |
PMID | 15113321
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Bacteremia
(epidemiology, microbiology)
- Catheterization, Central Venous
(adverse effects)
- Catheterization, Peripheral
(adverse effects)
- Colony Count, Microbial
- Gram-Negative Bacteria
(drug effects, isolation & purification)
- Gram-Negative Bacterial Infections
(epidemiology, microbiology)
- Gram-Positive Bacteria
(drug effects, isolation & purification)
- Gram-Positive Bacterial Infections
(epidemiology, microbiology)
- Greece
(epidemiology)
- Hospitals, University
- Humans
- Incidence
- Methicillin
(pharmacology)
- Methicillin Resistance
- Microbial Sensitivity Tests
- Retrospective Studies
- Staphylococcal Infections
(epidemiology, microbiology)
- Staphylococcus
(drug effects, isolation & purification)
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