Abstract | BACKGROUND: OBJECTIVE: METHODS: Epicutaneous skin prick test to cow's milk, CAP radioallergosorbent test, atopy patch tests, and double-blind, placebo-controlled milk challenge (DBPCMC) were performed. RESULTS: During initial presentation at 3 weeks of age, the circulating eosinophil count increased from 13,800/mm3 to 44,254/mm3 within 2 weeks while taking cephalexin. Despite treatment, he had worsening rash and FTT at 10 weeks of age with an IgE level of 8,454 U/mL. After changing from an infant milk formula with whey protein to an amino acid-based formula in combination with oral antibiotic treatment, his rash and growth velocity improved markedly within 2 months. IgE decreased to 2,747 U/mL. He remained clinically well for 12 months. He subsequently developed additional food and inhalant allergies with an increase in IgE to 12,150 U/mL. Cow's milk allergy was confirmed by epicutaneous skin prick test, atopy patch test, and DBPCMC. CONCLUSIONS:
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Authors | Vivian P Hernandez-Trujillo, William T Nguyen, Joseph T Belleau, Michael Jeng, Mary Ellen Conley, D Betty Lew |
Journal | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
(Ann Allergy Asthma Immunol)
Vol. 92
Issue 4
Pg. 469-74
(Apr 2004)
ISSN: 1081-1206 [Print] United States |
PMID | 15104201
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Milk Proteins
- Immunoglobulin E
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Topics |
- Double-Blind Method
- Humans
- Immunoglobulin E
(blood)
- Infant, Newborn
- Job Syndrome
(blood, complications, etiology)
- Male
- Milk Hypersensitivity
(blood, complications, etiology)
- Milk Proteins
(adverse effects)
- Radioallergosorbent Test
- Skin
(pathology)
- Skin Tests
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