Arterial blood gases with 700 ml tidal volumes during out-of-hospital CPR.

Abstract

The optimal tidal and minute ventilation during cardiopulmonary resuscitation (CPR) is not known. In the present study seven adult, non-traumatic, out-of-hospital cardiac arrest patients were intubated and mechanically ventilated at 12 min(-1) with 100% oxygen and a tidal volume of 700 ml (10 +/- 2 ml kg(-1)). Arterial blood gas samples were analysed after 6-8 min of unsuccessful resuscitation and mechanical ventilation. Mean PaCO2 was 5.2 +/- 1.3 kPa and mean PaO2 30.7 +/- 17.2 kPa. The patient with the highest (14 ml kg(-1)) and lowest (8 ml kg(-1)) tidal volumes per kg had the lowest and highest PaCO2 values of 2.6 and 6.8 kPa, respectively. Linear regression analysis confirmed a significant correlation between arterial pCO2 and tidal volume in ml/kg, r2 = 0.87. We conclude that aiming for an estimated ventilation of 10 ml kg(-1) tidal volume at frequency of 12 min(-1) might be expected to achieve normocapnia during ALS.

• Authors: E Dorph, L Wik, P A Steen
• Journal: Resuscitation (Resuscitation) Vol. 61 Issue 1 Pg. 23-7 (Apr 2004) ISSN: 0300-9572 [Print] Ireland
• PMID: 15081177 (Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Carbon Dioxide
• Oxygen

Topics

• Aged
• Aged, 80 and over
• Arteries
• Carbon Dioxide (blood)
• Cardiopulmonary Resuscitation (methods)
• Emergency Medical Services (methods)
• Female
• Heart Arrest (therapy)
• Humans
• Linear Models
• Male
• Middle Aged
• Oxygen (blood)
• Respiration, Artificial
• Tidal Volume