Cardiac transplantation in twins with autosomal dominant Emery-Dreifuss muscular dystrophy.

Abstract

Emery-Dreifuss muscular dystrophy (EDMD) is a neuromuscular disorder resulting in progressive muscle weakness, contractures, and cardiomyopathy. We report successful cardiac transplantation in identical twin brothers with autosomal dominant EDMD, complicated by ventricular arrhythmias and end-stage cardiomyopathy. Early recognition of progressive cardiac disease and subsequent cardiac transplantation are lifesaving in children with EDMD.

• Authors: Maryanne R Kichuk Chrisant, Jonathan Drummond-Webb, Sara Hallowell, Neil R Friedman
• Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation (J Heart Lung Transplant) Vol. 23 Issue 4 Pg. 496-8 (Apr 2004) ISSN: 1053-2498 [Print] United States
• PMID: 15063412 (Publication Type: Case Reports, Journal Article)

Topics

• Cardiomyopathy, Dilated (etiology, surgery)
• Child
• Diseases in Twins (surgery)
• Heart Transplantation
• Humans
• Male
• Muscular Dystrophy, Emery-Dreifuss (complications)
• Tachycardia, Ventricular (etiology, surgery)
• Twins, Monozygotic