Management of Frey's syndrome and hypersialorrhea with botulinum toxin.

Abstract

Botulinum toxin (BTX) is a safe and reliable drug for the treatment of Frey's syndrome and hypersialorrhea. Currently, the intradermal injection of BTX is the standard treatment of Frey's syndrome. A disappearance of Frey's syndrome for 1 to 1.5 year could almost be promised. Recently, BTX was introduced for the treatment of hypersialorrhea. Although some questions exist about the optimal dosage and the type of major salivary glands that should be treated, hypersialorrhea was reduced in almost all affected children and adults for up to 6 months by using ultrasound-guided intraglandular BTX injections.

• Authors: Orlando Guntinas-Lichius
• Journal: Facial plastic surgery clinics of North America (Facial Plast Surg Clin North Am) Vol. 11 Issue 4 Pg. 503-13 (Nov 2003) ISSN: 1064-7406 [Print] United States
• PMID: 15062255 (Publication Type: Journal Article, Review)

Chemical References

• Neuromuscular Agents
• Botulinum Toxins, Type A

Topics

• Botulinum Toxins, Type A (administration & dosage)
• Humans
• Injections
• Injections, Intramuscular
• Neuromuscular Agents (administration & dosage)
• Salivary Glands
• Sialorrhea (diagnosis, etiology, physiopathology, therapy)
• Sweating, Gustatory (diagnosis, etiology, physiopathology, therapy)